Patient Selection Initial Screening

All potential donor candidates must undergo an extensive medical and psychological evaluation in accordance with guidelines published by the American Society of Transplant Physicians (14-16).

Psychological evaluation includes a complete evaluation of the donor's emotional stability and determination if an altruistic motivation for donation exists.

A thorough laboratory evaluation is performed for histocompatibility testing and to ensure that the healthy donor will be left with normal renal function after nephrectomy. Standard blood testing includes ABO histocompatibility, HLA crossmatching, complete blood count, serum chemistries including liver function tests, and a coagulation profile.

The potential donor is also screened for viral exposure, including hepatitis profile and exposure to human immunodeficiency virus, cytomegalovirus, varicella, and Epstein-Barr virus. Urine testing includes urinalysis, urine culture, and a 24-hour urine collection analysis to evaluate urine protein levels and creatinine clearance. Female patients over age 40 must have a recent negative Papanicolaou cervical smear and negative screening mammogram.

0 0

Post a comment