Intracranial Lipoma Embryologic Origin

Intracranial Lipoma Sites

Theories regarding the pathogenesis of intracranial lipomas have evolved since the first report of a chiasmatic lipoma by Meckel in 1818.23 A contemporary consensus holds that intracranial lipomas result from the abnormal persistence and maldifferentiation of the meninx primitiva during the development of the subarachnoid space.20 This theory, first proposed by Verga in 1929 and well summarized and further supported by Truwit and Barkovich in 1990,20 accounts for several of the distinctive...