Infecting organisms can be subdivided into two types. Exogenous organisms
Exogenous organisms are organisms introduced into a wound from an external source. The two main exogenous organisms responsible for wound sepsis are Staphylococcus aureus and Streptococcus pyogenes. These are encountered much less frequently than they used to be, with the exception of patients with trauma and/or burns, in whom they are as prevalent as ever. When wound sepsis occurs with these bacteria, it usually indicates a breakdown of sterile surgical technique. The longer an operative procedure, the more likely the procedure is to become infected by an exogenous organism.
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