Cognitive Effects

Many patients with TSC experience comorbid learning, attentional, and developmental disorders. Those patients who do not meet strict criteria for ADHD nonetheless often demonstrate deficits in executive control processing that are associated with attention deficits and impaired goal-directed behavior. These individuals struggle to complete tasks that require planning, organization, monitoring, and judgment (Prather and De Vries 2004). Although approximately 50% of patients with TSC have IQs in the normal range, the remainder can be mildly to profoundly developmentally delayed. The risk of psychopathology is higher in those patients who are mentally retarded. There is no gender difference in the development of psychiatric disorders among patients with TSC. In addition, there are no known differences in physical findings between male and female patients.

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