Cognitive Effects

Research has consistently documented higher rates of cognitive deficits among children with SCD than among control populations. In some children, cognitive decrements of SCD are direct results of neurological damage from overt cerebrovascular accident (CVA) or silent cerebral infarcts (Armstrong et al. 1996). However, children with SCD and no history of CVA also frequently exhibit cognitive deficits compared with peers (Brown et al. 1993a; Schatz et al. 2002a). Table 17-1 summarizes the common cognitive effects of SCD based on patients' CVA history.

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