Developmental Pharmacokinetics and Pharmacodynamics

Developmental pharmacokinetics focuses on the measurable physical and chemical properties of medications as they are absorbed, distributed, metabolized, and eliminated by the human body at different ages (Robinson and Owen 2005). Pharmaco-dynamics outlines the mechanisms and clinical manifestations of a drug's pharmacological effects as exerted via drug-receptor binding and receptor function/signaling at the intracellular and intercellular levels. Developmental pharmacodynamic research is needed to learn how the ontology of brain anatomy, neural circuits, hormones, receptors, and neurotransmitters interacts with and influences responses to psychotropic drugs across the life span (Carrey and Dursun 1997).

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