The growing knowledge of the increased prevalence of depressive disorders among physically ill children and adolescents has not resulted in higher rates of recognition or treatment (Kessler et al. 2003). Well-controlled studies are emerging that support the efficacies of pharmacotherapy and psychotherapies for the treatment of depression in those patients affected by cancer, diabetes, HIV disease, heart disease, and neurological disorders. Despite the fact that these studies have focused predominately on adults, they provide direction for future investigation.

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