Definitive management of penile carcinomas is stage dependent. Due to the rarity of the disease there are no randomized prospective trials comparing the available treatment options. Since the development of larger supraregional treatment centres in the

UK, the utilization of penile-preserving techniques has improved. Such surgical techniques have been shown in this chapter to provide good oncological control while minimizing the functional and psychological morbidity often associated with conventional surgery and radiotherapy.

The vast majority of experts agree that stage Ta, T1, T2, and distal T3 tumors of all grades can be successfully treated with penile-preserving therapies. Careful case selection, based on both tumor and patient characteristics is required. Close follow-up is essential following penile preserving treatment as the local recurrence rate is higher compared to partial or total penectomy.

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