Contents

1 Epidemiology and Etiology of Penile Cancer 1

Maaike C.G. Bleeker, Daniƫlle A.M. Heideman, Peter J.F. Snijders, Simon Horenblas, and Chris J.L.M. Meijer

2 Molecular Biology of Penile Cancer 13

Daniƫlle A.M. Heideman, Maaike C.G. Bleeker, Hashim Uddin Ahmed, Manit Arya, Simon Horenblas, Peter J.F. Snijders, and Chris J.L.M. Meijer

3 Diagnosis and Pathology of Penile Cancer 27

Alcides Chaux and Antonio L. Cubilla

4 Radiological Imaging in Penile Cancer 69

Alex P.S. Kirkham

5 Premalignant Lesions of the Penis 103

Majid Shabbir, Nicholas A. Watkin, and Asif Muneer

6 Management of Penile Cancer Using

Penile-Preserving Techniques 125

Paul Hadway, Peter R. Malone, Suks Minhas, and Asif Muneer

7 Management of Locally Advanced and Metastatic Penile Cancer 143

Asif Muneer, Afshin Mosahebi, Vijay Sangar, and Suks Minhas

8 Cancer of the Male Urethra 167

Raj Nigam, Usama Ahmed, Alex Freeman, Suks Minhas, and Asif Muneer

9 Management of Lymph Nodes 183

Niels M. Graafland and Simon Horenblas

10 Prognostic Indicators in Penile Cancer 215

Vincenzo Ficarra, Giacomo Novara, Guido Martignoni, and Filiberto Zattoni

11 Phallic Reconstruction Following

Surgery for Penile Cancer 237

David J. Ralph

12 The Role of Chemotherapy and Radiotherapy in the Treatment of Penile Cancer 259

Jan M. Kerst, Luc M.F. Moonen, Niels M. Graafland, Andries M. Bergman, Floris J. Pos, and Simon Horenblas

13 Nanotechnology and the Implications for Penile Cancer 273

Ammar Hameed, Iqbal S. Shergill, and Manit Arya

14 Follow-Up of Patients with Penile Cancer 283

Niels M. Graafland and Simon Horenblas

15 Living with Penile Cancer: Effects on

Psychology and Quality of Life 291

Ian Eardley and Victor Palit

16 Future Directions in Penile Cancer 301

Paul K. Hegarty and Curtis A. Pettaway

Appendix 319

Index

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