Epidemiology of Penile Cancer

Penile cancer occurs predominantly in elderly men although the disease may also occasionally present in young men. The mean age at diagnosis of patients with penile cancer is 60 years and the age-related incidence is highest at 70 years. The incidence has remained stable over recent years with an age-standardized incidence of 0.3-1.0 per 100,000 in Western Europe and the United States, accounting for 0.4-0.6% of all malignancies in this part of the world.1,2 The incidence is significantly higher is some areas of Asia, Africa, and South America, where the disease can constitute up to 10% of malignant disease in men with incidence rates of 4.2 and 4.4 per 100,000 in Paraguay and Uganda, respectively.3,4 In terms of the annual number of penile cancers occurring globally, a total penile cancer burden of about 26,000 cases has been estimated.5 The substantial worldwide variation in penile cancer incidences is most likely due to the differences in socio-economic conditions and religious practices.6

Department of Pathology, Free University Medical Center, Amsterdam 1081 HV, The Netherlands

A. Muneer et al. (eds.), Textbook of Penile Cancer,

DOI 10.1007/978-1-84882-879-7_1, © Springer-Verlag London Limited 2012

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