Molecular Prognostic Factors

Several molecular biomarkers have been evaluated as prognostic factors for penile cancer 1 59,160 including cell cycle-related proteins, such as p53, pl6INK4a, p21, Ki-67, and PCNA62,137,161-167 and proteins associated with tumor progression, such as E-cadherin, telomerase activity, matrix metalloproteinases, COX-2, and PGE synthase-1. i 37,168-170 Genetic imbalances, ploidy status, and specific proto-oncogenes mutations were addressed as well.171-176 However, none of the aforementioned biomarkers has a clear and defined utility in the management of patients with penile cancer.

Dealing With Erectile Dysfunction

Dealing With Erectile Dysfunction

Whether you call it erectile dysfunction, ED, impotence, or any number of slang terms, erection problems are something many men have to face during the course of their lifetimes.

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