Patterns of Recurrence

The majority of recurrences in penile carcinoma develop within 5 years after the primary treatment. Within this the largest proportion will occur within 2 years after the initial treatment. The interval between treatment and recurrence seems to be dependent on the type of relapse. Recent data from a large two-institutional retrospective study involving 700 patients has shown that 66% of local recurrences, 86%

Department of Urology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands

Fig. 14.1 Cumulative risk of recurrence (in patients with a simultaneous local and

Fig. 14.1 Cumulative risk of recurrence (in patients with a simultaneous local and regional or distant recurrence, the local recurrence was taken into account). (Adapted from Leijte et al.1)

0-700 523 365 279 224 168 132 98

0 6 12 18 24 30 36 42 48 54 60 66 72 78 84 Time from diagnosis regional or distant recurrence, the local recurrence was taken into account). (Adapted from Leijte et al.1)

0-700 523 365 279 224 168 132 98

0 6 12 18 24 30 36 42 48 54 60 66 72 78 84 Time from diagnosis of regional recurrence, and all distant recurrences were detected within the first 2 years, respectively (see Fig. 14.1 and Table 14.1).1 Consequently, follow-up should be intense during the first 2 years after surgery. A maximal follow-up of 5 years seems reasonable to detect the majority of recurrences. Similar to other types of solid tumors, a second primary tumor could develop because the remaining epithelium of the glans of the penis remains "at risk" for developing a malignancy or because of prolonged exposure to an etiological factor (i.e. HPV infection) when penile-preserving surgery has been performed.

Dealing With Erectile Dysfunction

Dealing With Erectile Dysfunction

Whether you call it erectile dysfunction, ED, impotence, or any number of slang terms, erection problems are something many men have to face during the course of their lifetimes.

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