Resection Margins

Since the presence of local recurrence is associated with an increased risk for regional metastasis and systemic dissemination 156 it is crucial to obtain negative resection margins to avoid this event in patients treated by surgery.157 The sites of margin involvement include Buck's fascia and urethral/periurethral tissues with surrounding corpus spongiosum while corpora cavernosa and the penile shaft skin are less frequently compromised. 1 58 Evaluation of surgical margins in a penectomy specimen should include submission of both corpora cavernosa as well as distal urethra, shaft skin, and Buck's fascia. In circumcision and wide excision, the specimen margins should be inked and completely submitted.

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