Acute Gout

• Monitor the patient for pain relief and decreased swelling of the affected joints. Both parameters should be improved significantly within 48 hours of starting acute gout therapy.

• Assess the patient's subjective complaints and objective information for adverse effects. For NSAID therapy, be alert for new-onset epigastric pain, dark or tarry stools, blood in vomitus, dizziness or lightheadedness, development of edema, decreased urine output by more than 50% over a 24-hour period, or shortness of breath. For colchicine, monitor for nausea or vomiting, diarrhea, easy bruising, cold or flulike symptoms, lightheadedness, muscle weakness, or pain. Counsel the patient to inform you of any new medications started or stopped while taking colchicine.

• Monitor patients receiving intra-articular corticosteroid injections for increased swelling or pain at the injection site.

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