Advantages

1. More hemodynamic stability (blood pressure) due to slow ultrafiltration rate

2. Increased clearance of larger solutes, which may explain good clinical status in spite of lower urea clearance

3. Better preservation of residual renal function

4. Convenient intraperitoneal route of administration of drugs such as antibiotics and insulin

5. Suitable for elderly and very young patients who may not tolerate hemo-dialysis well

6. Freedom from the "machine" gives the patient a sense of independence (for continuous ambulatory peritoneal dialysis)

7. Less blood loss and iron deficiency, resulting in easier management of anemia or reduced requirements for erythropoietin and parenteral iron

8. No systemic heparinization requirement

9. Subcutaneous versus IV erythropoietin or darbepoetin is usual, which may reduce overall doses and be more physiologic

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