Anthracyclines

All the anthracyclines contain a four-membered anthracene ring, a chromophore, with an attached sugar portion. Free radicals formed from the anthracyclines combine with oxygen to form superoxide, which can make hydrogen peroxide. Oxygen-free-radical formation is a cause of cardiac damage and extravasation injury, which is common to these drugs. Daunorubicin, doxorubicin, epirubicin, and idarubicin cause cardiac toxicity, as manifested by a congestive heart failure/cardiomyopathy symptomotology, mucositis, and myelosuppression. These drugs are vesicants; significant tissue damage may occur with extravasation.

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Stop Headache Drug Free

If you are suffering from headaches, you can make the pain stop just by following some basic but little known principles. Take 15 minutes browsing through this guide and you'll find dozens of tips to gain control in the battle against headache pain.

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