Chronic Transfusion Therapy

Chronic transfusion therapy is warranted to prevent serious complications from SCD, including stroke prevention and recurrence. Especially in children, chronic transfusions have been shown to decrease stroke recurrence from approximately 50% to 10% over 3 years. Without chronic transfusions, approximately 70% of ischemic stroke patients will have another stroke. Chronic transfusion therapy also may be used to prevent vasoocclusive pain and ACS, as well as prevent progression of organ damage. Patients receiving chronic transfusion therapy report increased energy levels, improved quality of life, and better exercise tolerance. Patients in whom chronic transfusion therapy should be considered, include those with severe or recurrent ACS, debilitating pain, splenic sequestration, recurrent priapism, chronic organ failure, transient ischemic attacks, abnormal transcranial Doppler studies, intractable leg ulcers, severe chronic anemia in the presence of cardiac failure, and complicated pregnancies.5,9

Your Heart and Nutrition

Your Heart and Nutrition

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