Clinical Presentation and Diagnosis of SCD General

• Indentified by neonatal screening before 2 months of age Symptoms

• Painful vasoocclusive crises are the hallmark of SCD

• Dactylitis (hand-foot syndrome) before age 1 year

• May develop infarction of the spleen, liver, bone marrow, kidney, brain, and lungs

• Gallstones

• Priapism in males

• Slow healing lower extremity ulcers after trauma or infection

• Weakness, fatigue Signs

• Chronic hemolytic anemia is common

• Enlargement of spleen, and heart

• Scleral icterus Laboratory Tests

• Hgb 7 to 10 g/dL (70-100 g/L or 4.3-6.2 mmol/L)

• Low HgF and increased reticulocytes, platelets, and WBCs

• Presence of sickled cells on blood smear (see Fig. 68-2)

• Neonatal screening: hemoglobin electrophoresis, isoelectric focusing, or DNA analysis

Reducing Blood Pressure Naturally

Reducing Blood Pressure Naturally

Do You Suffer From High Blood Pressure? Do You Feel Like This Silent Killer Might Be Stalking You? Have you been diagnosed or pre-hypertension and hypertension? Then JOIN THE CROWD Nearly 1 in 3 adults in the United States suffer from High Blood Pressure and only 1 in 3 adults are actually aware that they have it.

Get My Free Ebook


Post a comment