Clinical presentation and diagnosis

The clinical presentation of osteomyelitis may vary depending on route and duration of infection, as well as patient-specific factors such as infection site, age, and comorbidities. In hematogenous osteomyelitis, the patient typically experiences systemic

and localized signs and symptoms. ' ' ' In comparison, patients with chronic infection typically present with only localized signs and symptoms. A cardinal sign of

chronic osteomyelitis is the formation of sinus tracts with purulent drainage. '

FIGURE 81-3. Pathogenesis of osteomyelitis.
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