D7score Is the number of standard deviations above or below the mean bone mineral density in young adults

Laboratory Evaluation

Laboratory assessment has little value in diagnosing osteoporosis, but it can be beneficial in identifying or excluding secondary causes of bone loss, such as hyperparathyroidism, low 25-hydroxyvitamin D levels, hyperthyroidism, hypogo-nadism, or cancer.8 Biochemical markers of bone turnover such as pyridinoline, deoxypyridinoline, N-telopeptides, and C-telopeptides of Type I collagen cross-links have been associated with an increased fracture risk in some trials. Variations in the normal ranges of these tests may be related to age, gender, food, and diurnal variation,

making interpretation of these tests difficult. For these reasons, biochemical markers of bone turnover are not recommended for diagnosis of osteoporosis.

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