• Metallic taste Signs

Signs vary depending on the type of OPC:

• Diffuse erythema on the surface of buccal mucosa, throat, tongue, and gums.

• White patches on tongue, gums, or buccal mucosa; removal of patches reveals erythematous and bloody tissue; ability to remove patches distinguishes OPC from oral hairy leukoplakia.

• Angular cheilitis presents with small cracking lesions, erythema, and soreness at the corners of the mouth; associated with vitamin and iron deficiency.

• Denture stomatitis presents with flat, red lesions on mucosa beneath dentures; signs of chronic erythema and edema on mucosa.

• Hyperplastic OPC presents with discrete, transparent raised lesions on the inner mucosa of the cheek; typically found in men who smoke.

• Pseudomembranous OPC presents with yellow-white plaques that may be small and discrete or confluent; most common form found in HIV patients.

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