Enhancement of Lactation

Optimization of breast-feeding techniques is the first approach when decreased lactation is suspected. No drugs are currently approved by the FDA for lactation enhancement, but dopamine antagonists, metoclopramide and domperidone, are sometimes

used for this purpose. The efficacy of metoclopramide is controversial. Maternal side effects include fatigue, irritability, abdominal pain, extrapyramidal symptoms, and depression (with long-term use). No side effects in the infant have been reported. Increased milk production should be observed within 2 to 5 days. The drug should be taken for 1 to 2 weeks and then tapered by 10 mg/day at weekly intervals. The efficacy of domperidone is also controversial, but side effects are infrequent, as domperidone does not cross the blood-brain barrier. However, domperidone is not available in the United States, and the FDA issued a warning against domperidone use in 2004 owing to reports of cardiac arrhythmia, myocardial infarction, and sudden death associated with high IV doses prescribed for gastric disorders in patients with electrolyte disturbances and complex disease states. 3

New Mothers Guide to Breast Feeding

New Mothers Guide to Breast Feeding

For many years, scientists have been playing out the ingredients that make breast milk the perfect food for babies. They've discovered to day over 200 close compounds to fight infection, help the immune system mature, aid in digestion, and support brain growth - nature made properties that science simply cannot copy. The important long term benefits of breast feeding include reduced risk of asthma, allergies, obesity, and some forms of childhood cancer. The more that scientists continue to learn, the better breast milk looks.

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