Fever is the most frequently reported adverse effect in children and adolescents. Fever associated with vaccination is defined as a temperature of greater than or equal to 38°C (100.4°F) measured at any site using a validated device. Fever is caused by a complex reaction induced by the production of cytokines that affect the hypothalamic neurons. This results in raising the hypothalamic set point. Temperature elevations above 40°C (104°F) can result in cellular and multi-organ dysfunction. Excessive temperature elevations rarely result from fever alone, but are usually coupled with other

thermoregulatory dysfunction.

The whole cell pertussis vaccine has been highly associated with temperature elevations; however, the prevalence has significantly decreased since the introduction of the acellular pertussis vaccine. Live virus vaccines are also associated with fever.

Reducing Blood Pressure Naturally

Reducing Blood Pressure Naturally

Do You Suffer From High Blood Pressure? Do You Feel Like This Silent Killer Might Be Stalking You? Have you been diagnosed or pre-hypertension and hypertension? Then JOIN THE CROWD Nearly 1 in 3 adults in the United States suffer from High Blood Pressure and only 1 in 3 adults are actually aware that they have it.

Get My Free Ebook

Post a comment