General Approach to Treatment

To treat nausea and vomiting most effectively, it is important to first identify the underlying cause of the symptoms. Treating the cause (if possible) will in turn eliminate the nausea and vomiting.

Profuse or prolonged vomiting can lead to complications ofdehydration and metabolic abnormalities. Patients must have adequate hydration and electrolyte replacement orally (if tolerated) or IV to prevent and correct these problems. Some pharmacologic treatments work locally in the GI tract (e.g., antacids and prokinetic agents), whereas others work in the CNS (e.g., antihistamines and anticholinergics).1

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