General Approach to Treatment Including Nonantimicrobial Treatment

While selection of antimicrobial therapy may be a major consideration in treating infectious diseases, it may not be the only therapeutic intervention. Other important therapies may include adequate hydration, ventilatory support, and other supportive medications. In addition, antimicrobials are unlikely to be effective if the process or source that leads to the infection is not controlled. Source control refers to this process and may involve removal of prosthetic materials such as catheters and infected tissue or drainage of an abscess. Source control considerations should be a fundamental component of any infectious diseases treatment. It is also important to recognize that there may be many different antimicrobial regimens that may cure the patient. While the following therapy sections provide factors to consider when selecting antimicrobial regimens, an excellent and more in-depth resource for selecting antimicrobial regimens for a variety of infectious diseases is the Infectious Diseases Society of America Guidelines.7

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