Gonorrhea is a curable STI caused by the gram-negative diplococcus Neisseria gonorrhoeae. Proper therapeutic management with antimicrobial agents is essential to eradicate this infection and prevent the development of associated sequelae such as a urethritis, cervicitis, or dysuria.

In the United States, the highest rate of gonococcal infection is seen within the 15-to 24-year-old age groups for both sexes; although more cases are reported in men. Approximately 600,000 new cases occur annually in the United States. Factors associated with an increased risk of infection include ethnicity, low socioeconomic status, and illicit drug use. The risk of a cervical infection after a single episode of vaginal intercourse is approximately 50% and increases with multiple exposures. Furthermore, rates of reinfection are significantly higher among ethnic minorities.

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