HF With Preserved LVEF

It is now recognized that a significant number of patients exhibiting HF symptoms have normal systolic function or preserved LVEF (40-60%). It is believed that the primary defect in these patients is impaired ventricular relaxation and filling, commonly referred to as diastolic dysfunction or diastolic HF. HF with preserved EF is more prevalent in older women and is closely associated with hypertension or diabetes, and to a lesser extent, CAD and atrial fibrillation.44 Morbidity in HF patients with preserved EF is comparable to those with depressed EF, as both are characterized by frequent, repeated hospitalizations.44 However, HT with preserved TT is associated with better survival. The diagnosis is based on findings of typical signs and symptoms of HT, in conjunction with echocardiographic evidence of normal LV systolic function and no valvular disease.

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