Immunosuppressive Therapies Treatment of Acute Rejection Episodes

Acute rejection is generally treated with a course of high-dose methylprednisolone (250-1,000 mg/day IV for 3 days), which is usually sufficient to ameliorate the rejection episode. If the acute rejection episode is resistant to the initial course of steroids, a second course may be administered or the patient may begin therapy with antithy-mocyte globulin (1.5 mg/kg/day for 3-14 days). Acute rejection refractory to these treatments may require OKT-3. However, the use of this agent has fallen out of favor due to the severe short- and long-term adverse events associated with its use.

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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