Key concepts

© Ovarian cancer is a sporadic disease, less than 10% of ovarian cancers can be attributed to heredity.

Because CA-125 is a nonspecific marker, there is no standard recommendation for routine screening for prevention of ovarian cancer.

Ovarian cancer is denoted "the silent killer" because of the nonspecific signs and symptoms.

Surgery is the primary treatment intervention for ovarian cancer.

® Ovarian cancer is staged surgically using the International Federation of Gyneco logy and Obstetrics (FIGO) staging algorithm.

After initial surgery, the gold standard of care is six cycles of a taxane/platinum-containing regimen.

Although majority of patients will initially achieve a complete response (CR), more than 50% will recur within the first 2 years.

Because the efficacy of the agents is similar, the selection of agent for treatment of recurrent platinum-resistant ovarian cancer is dependent upon residual toxicit-ies, physician preference, and patient convenience.

O Precaution should be used in removal of ascites because of the potential complications associated with rapid fluid shifts.

© In ovarian cancer patients, small bowel obstruction (SBO) is a common complication of progressive disease (PD). In general, laxatives should not be used in patients with SBOs.

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