Laboratory Testing

• Increased D-dimer

• Thrombocytopenia

• Decreased fibrinogen

• Increased fibrin degradation products (FDP)

• Increased prothrombin time (PT)

• Evidence of end-organ dysfunction or failure

Heparin may be given IV or subcutaneously; there is no universally accepted dose. Heparin administered subcutaneously for venous thromboembolism prophylaxis (5,000 units every 8-12 hours) can be beneficial in DIC patients without serious or life-threatening bleeding. Full-dose heparin therapy in adults is a bolus of 5,000 units, followed by a continuous infusion of 1,000 units/h. In general, full-dose heparin should be avoided in patients with DIC due to increased risk of bleeding, and a lower dose of 500 units/hour can be used. Since the aPTT is already elevated in individuals with DIC, monitoring heparin therapy may be difficult. Treatment with subcutaneous

heparin and low-molecular weight heparins are other, less studied options.

Anxiety and Depression 101

Anxiety and Depression 101

Everything you ever wanted to know about. We have been discussing depression and anxiety and how different information that is out on the market only seems to target one particular cure for these two common conditions that seem to walk hand in hand.

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