Mucosal Resistance

The esophageal mucosa and submucosa consist of mucus-secreting glands that contain bicarbonate. Bicarbonate moving from the blood to the lumen can neutralize acidic refluxate in the esophagus. A decrease in this normal defense mechanism can potentially lead to erosions in the esophagus. When the mucosa is repeatedly exposed to the refluxate in GERD, or if there is a defect in the normal mucosal defenses, hydro-genions diffuse into the mucosa, leading to the cellular acidification and necrosis that ultimately cause esophagitis.4

Herbal Remedies For Acid Reflux

Herbal Remedies For Acid Reflux

Gastroesophageal reflux disease is the medical term for what we know as acid reflux. Acid reflux occurs when the stomach releases its liquid back into the esophagus, causing inflammation and damage to the esophageal lining. The regurgitated acid most often consists of a few compoundsbr acid, bile, and pepsin.

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