Outcome Evaluation

• To determine the efficacy of nonpharmacologic and pharmacotherapy for both STE and NSTE ACS, monitor patients for: (a) relief of ischemic discomfort; (b) return of ECG changes to baseline; and (c) absence or resolution of heart failure signs.

• Monitoring parameters for recognition and prevention of adverse effects from ACS pharmacotherapy are described in Table 8-4. In general, the most common adverse reactions from ACS therapies are hypotension and bleeding. To treat for bleeding and hypotension, discontinue the offending agent(s) until symptoms resolve. Severe bleeding resulting in hypotension secondary to hypovolemia may require blood transfusion.

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