Outcome evaluation

Early breast cancer is resected completely with curative intent, and adjuvant chemotherapy and hormonal therapy are initiated to prevent recurrence. During adjuvant chemotherapy, laboratory values to monitor chemotherapy toxicity are obtained prior to each cycle of chemotherapy. After completion of adjuvant therapy, patients are monitored every 3 months for the first few years after diagnosis, with intervals between exams extended as time from diagnosis lengthens.

• Physical examination to detect breast cancer recurrence

• Annual mammography

• Symptom-directed workup

Locally advanced breast cancer often is treated with neoadjuvant therapy to make the tumor surgically resectable.

During neoadjuvant chemotherapy, laboratory values to monitor chemotherapy toxicity are obtained prior to each cycle of chemotherapy, and a physical and ultrasound examinations to detect size of tumor are performed after the cycles of neoad-juvant therapy are completed. After a complete surgical resection, monitoring proceeds as described earlier for early breast cancer.

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