Outcome evaluation

• Patients should notice symptomatic relief within 2 to 3 days of initiating therapy. Complete resolution typically occurs within 7 to 10 days. The entire course of therapy should be continued even if symptoms have resolved. If the condition does not resolve or worsens, the patient should be referred to a specialist for aggressive therapy.

• Short courses of oral azoles are associated with GI upset, while courses lasting longer than 7 to 10 days are associated with increased risk of hepatotoxicity. In patients receiving prolonged therapy lasting more than 3 weeks, periodic monitoring of liver function tests should be considered.

• Immunocompetent patients generally do not require reassessment after treatment. Patients with neutropenia exhibit an increased risk of dissemination of infection, and therefore should be monitored for signs of systemic fungal infection. Due to an increased risk of recurrence, HIV-positive patients should routinely be evaluated for recurrence at each visit.

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