Outcome Evaluation

• The successful outcome in cholesterol management is to reduce cholesterol and triglycerides below the NCEP ATP III goals in an effort to alter the natural course of atherosclerosis and decrease future cardiovascular events.

• Employ an adequate trial ofTLC in all patients, but institute pharmacotherapy concurrently in higher-risk patients.

• When indicated, initiate drug therapy at a dose that will reduce LDL cholesterol in the range of 30% to 40%.

• Typically, statins are the medications of choice to treat high LDL cholesterol because of their ability to substantially reduce LDL cholesterol, ability to reduce morbidity and mortality from atherosclerotic disease, convenient once-daily dosing, and low risk of side effects.

• Employ an individualized patient monitoring plan in an effort to minimize side effects and maintain treatment adherence and lipid goals.

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