Outcome evaluation

Monitor patients with CNS infections continuously throughout their treatment course to evaluate their progress toward achieving treatment goals, including relief of symptoms, eradication of infection, and reduction of inflammation to prevent death and the development of neurologic deficits. These treatment goals are best achieved by appropriate parenteral antimicrobial therapy, including empirical therapy to cover the most likely pathogens, followed by directed therapy after culture and sensitivity results are known. Components of a monitoring plan to assess efficacy and safety of antimi crobial therapy of CNS infections include clinical signs and symptoms and laboratory data (such as CSF findings, culture, and sensitivity data).

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