Outcome Evaluation

• Short-term goals are to safely achieve reduction in BP through the iterative process of employing drug therapy, along with nondrug therapy or lifestyle changes.

• Lifestyle changes should address other risk factors for CVD including obesity, physical inactivity, insulin resistance, dyslipidemia, smoking cessation, and others.

• Monitoring for efficacy, adverse events, and adherence to therapy is key to achieving the long-term goals of reducing the risk of morbidity and mortality associated with CVD.

Abbreviations Introduced in This Chapter

ACC/AHA ACCOMPLISH

ACE ACE-I

A-HcIT AIRE

ALLHAT

AMI ANBP2

ASCOT-BPLA

BHAT

CAGE

American College of Card iology/ American Heart Association Avoiding Cardiovascular Hvcnts in Combination Therapy in Patients Living with Systolic Hypertension Angiotensin-converting enzyme Angiotensin-Converting enzyme inhibitor

African American Heart Failure trial Acute Infarction Ramipril Efficacy Study

Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial

Acute myocardial infarction Australian-New Zealand Blood Pressure-2 study Angiotensin-receptor blocker Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm study Angiotcnsin-1 Angiotensin-2

/^-Blocker Heart Attack Trial Blood urea nitrogen Chymostatin-sensitive II-generating enzyme

CAPRICORN

Captopril Trial

CCBA CHARM

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