Pathogenesis

The infectious dose of EHEC is very low, between 1 and 100 colony-forming units (CFUs).11 The two major virulence factors for EHEC are the production of two Shiga-like cytotoxins (Shiga toxin [Stx] I and II) and adhesion-causing attachment-efface-ment (A/E) lesions. These Stx cytotoxins are responsible for vascular damage and systemic effects such as HUS. Adhesion mediates initial attachment of EHEC to intestinal epithelial cells. Following attachment, these organisms produce A/E lesions on individual intestinal epithelial cells. A/E lesions infect the small or large intestine and cause diarrhea.

Lose Weight Today With Yoga

Lose Weight Today With Yoga

Want to lose weight but don't know where to start? Transform Your Life With The Knowledge Of The Yogi's And Begin Losing Weight Today. This guide is one of the most valuable resources you can have when learning about yoga to lose weight.

Get My Free Ebook


Post a comment