The classical concept of mucositis pathophysiology asserts that direct cytotoxicity from chemotherapy or radiation to basal epithelial cells results in ulcerative lesions due to a lack of regeneration. These lesions are further complicated by trauma and/ or microorganism growth. However, the most recent theory of mucositis patho-physiology is more detailed, and involves a multistage, dynamic process that builds

upon the historical model. According to this theory, there are five stages of mucositis: initiation, primary damage response, signal amplification, ulceration, and healing. It is important to note that these stages do not occur sequentially. Rather, they are dynamic and may overlap.

The Prevention and Treatment of Headaches

The Prevention and Treatment of Headaches

Are Constant Headaches Making Your Life Stressful? Discover Proven Methods For Eliminating Even The Most Powerful Of Headaches, It’s Easier Than You Think… Stop Chronic Migraine Pain and Tension Headaches From Destroying Your Life… Proven steps anyone can take to overcome even the worst chronic head pain…

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