The classical concept of mucositis pathophysiology asserts that direct cytotoxicity from chemotherapy or radiation to basal epithelial cells results in ulcerative lesions due to a lack of regeneration. These lesions are further complicated by trauma and/ or microorganism growth. However, the most recent theory of mucositis patho-physiology is more detailed, and involves a multistage, dynamic process that builds

upon the historical model. According to this theory, there are five stages of mucositis: initiation, primary damage response, signal amplification, ulceration, and healing. It is important to note that these stages do not occur sequentially. Rather, they are dynamic and may overlap.

Anxiety and Depression 101

Anxiety and Depression 101

Everything you ever wanted to know about. We have been discussing depression and anxiety and how different information that is out on the market only seems to target one particular cure for these two common conditions that seem to walk hand in hand.

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