Pathophysiology

Viruses enter the upper respiratory tract mucosa via inhalation of aerosols or infected droplets or direct contact with contaminated secretions. After cell entry, viral replication and shedding occur for several days to weeks. Clinical symptoms are a result of epithelial cell damage, inflammation, vasodilation, edema from increased vascular permeability, increased mucus production, and impaired mucociliary clearance from neutrophil migration, cytokine release, and cytotoxic immune responses.42,45

Tracheobronchial inflammation and irritation induce cough via afferent nerve impulse

transmission to the medulla. Antibody production halts viral replication and inflammation as symptoms wane.

How To Bolster Your Immune System

How To Bolster Your Immune System

All Natural Immune Boosters Proven To Fight Infection, Disease And More. Discover A Natural, Safe Effective Way To Boost Your Immune System Using Ingredients From Your Kitchen Cupboard. The only common sense, no holds barred guide to hit the market today no gimmicks, no pills, just old fashioned common sense remedies to cure colds, influenza, viral infections and more.

Get My Free Audio Book


Post a comment