O1 The pathophysiology of primary hypertension is heterogeneous, but ultimately exerts its effects through the two primary determinants of BP: cardiac output (CO) and peripheral resistance (PR). The processes influencing these two determinants are numerous and complex (Fig. 5—2).9 The underlying cause of primary hypertension is unknown and most likely multifactorial. Although numerous hypotheses exist, an in-depth review of these is beyond the scope of this text and the reader is referred to additional texts for more information including discussion on the pathophysiology behind secondary causes of hypertension.10

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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