Patient Care and Monitoring

1. Assess the patient's symptoms and laboratory test results to determine if patient-directed therapy is appropriate.

2. Obtain a thorough history of prescription, nonprescription, and natural drug product use.

3. Educate the patient on lifestyle modifications that will reduce the risk of recurrent infections.

4. Develop a plan to assess the effectiveness of antimicrobial therapy.

5. Evaluate the patient for the presence of adverse drug reactions, drug allergies, and drug interactions (Table 81-3).

6. Stress the importance of adherence to the therapeutic regimen.

7. Provide patient education with regard to disease state and drug therapy. Explain the following:

• Causes of osteomyelitis

• Complications associated with osteomyelitis

• The drug, dose, duration, and route of administration of the patient's antimicrobial regimen

• Optimal medication administration time for the patient's lifestyle and other concurrent medications

• Available options for missed dose(s)

• Adverse effects that may occur

• Provide patient education monographs for antibiotic(s)

Abbreviations Introduced in This Chapter

BUN Blood area nitrogen

CRP C-reactive protein

CPK Creatine phosphokinase

CYP Cytochrome P-450 isoenzyme

D-test Disk diffusion test

ES R Erythrocyte sedi menta I ion ra I e

IVDA Intravenous drug abuser

LFT Liver function test

MAO Monoamine oxidase

MIC Minimum inhibitory concentration

M LS Mac rol id e - li ncosa triid e -s t rep togr amin

MRSA Methicillin-resistant Staphylococcus aureus

MSSA Methicillin-sensitive 5. aureus

PVD Peripheral vascular disease

Scr Serum creatinine

TM P - SMX Tr i m et ho pr i in ■ sul fa me t hoxa zole

UTI Urinary tract infection

Self-assessment questions and answers are available at ht-tp://www. mhpharmacotherapy. com/pp.html.

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