1. Assess the patient's symptoms and laboratory test results to determine if patient-directed therapy is appropriate.
2. Obtain a thorough history of prescription, nonprescription, and natural drug product use.
3. Educate the patient on lifestyle modifications that will reduce the risk of recurrent infections.
4. Develop a plan to assess the effectiveness of antimicrobial therapy.
6. Stress the importance of adherence to the therapeutic regimen.
7. Provide patient education with regard to disease state and drug therapy. Explain the following:
• Causes of osteomyelitis
• Complications associated with osteomyelitis
• The drug, dose, duration, and route of administration of the patient's antimicrobial regimen
• Optimal medication administration time for the patient's lifestyle and other concurrent medications
• Available options for missed dose(s)
• Adverse effects that may occur
• Provide patient education monographs for antibiotic(s)
Abbreviations Introduced in This Chapter
BUN Blood area nitrogen
CRP C-reactive protein
CPK Creatine phosphokinase
CYP Cytochrome P-450 isoenzyme
D-test Disk diffusion test
ES R Erythrocyte sedi menta I ion ra I e
IVDA Intravenous drug abuser
LFT Liver function test
MAO Monoamine oxidase
MIC Minimum inhibitory concentration
M LS Mac rol id e - li ncosa triid e -s t rep togr amin
MSSA Methicillin-sensitive 5. aureus
PVD Peripheral vascular disease
Scr Serum creatinine
TM P - SMX Tr i m et ho pr i in ■ sul fa me t hoxa zole
Self-assessment questions and answers are available at ht-tp://www. mhpharmacotherapy. com/pp.html.
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