Patient History

• History of present illness

• Comorbidities

• Current medications

• Previous antibiotic exposure (may provide clues as to colonization or infection with new specific pathogens or pathogens that may be resistant to certain antimicrobials)

• Previous hospitalization or health care utilization (also a key determinant in selecting therapy because the patient may be at risk for specific pathogens and/or resistant pathogens)

• Travel history

• Social history

• Pet/animal exposure

• Occupational exposure

• Environmental exposure Physical Findings

• Findings consistent with an infectious etiology?

• Body system abnormalities (e.g., rales, altered mental status, localized inflammation, erythema, warmth, edema, pain, and pus)

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