Pharmacologic Therapy437

Adults Recommended adult regimens include: Metronidazole 500 mg orally twice daily for 7 days or metronidazole gel (0.75%), one full applicator (5 g) intravaginally once daily for 5 days or clindamycin cream (2%), one full applicator (5 g) intravaginally at bedtime for 7 days.

Alternative regimens include: Clindamycin ovules 100 mg intravaginally once at bedtime for 3 days or clindamycin 300 mg orally twice daily for 7 days.

Pregnancy Pregnant symptomatic women should receive treatment. Treatment of BV in asymptomatic women at high-risk for preterm delivery with a recommended oral regimen mitigates preterm delivery. Screening should be performed during the first prenatal visit. Recommended regimens for pregnant women include: metronidazole 500 mg orally twice daily for 7 days or metronidazole 250 mg orally three times daily for 7 days or clindamycin 300 mg orally twice daily for 7 days.

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