^ Women who have an intact uterus should be prescribed a progestogen in addition to estrogen in order to decrease the risk of endometrial hyperplasia and endometrial cancer. 1 Progestogens should be prescribed for at least 12 to 14 days of the month and often are prescribed continuously. Low doses of oral estrogen therapy, as well as some vaginal preparations, require daily or intermittent administration of a progestogen in order to provide endometrial protection. Table 50-1 lists estrogen and progestogen preparations and dosages.

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