Remission Induction

The goal of induction chemotherapy in AML is essentially identical to that in ALL: "Empty" the bone marrow of all hematopoietic precursors, and allow repopulation with normal cells. The combination of an anthracycline (e.g., daunorubicin, doxoru-bicin, or idarubicin) and the antimetabolite cytarabine forms the backbone of AML induction therapy. The most common induction regimen (7 + 3) combines daunorubicin for 3 days with cytarabine on days 1 to 7. The remission rate for this combination is approximately 80% in children and younger adults but declines to 40% to 50% in patients older than 60 years of age.6 Despite studies that have used alternative anthra-cyclines or substituted high-dose for conventional-dose cytarabine and added etopos-ide and/or thioguanine, the 7 + 3 regimen remains the standard induction regimen.

Lose Weight Today With Yoga

Lose Weight Today With Yoga

Want to lose weight but don't know where to start? Transform Your Life With The Knowledge Of The Yogi's And Begin Losing Weight Today. This guide is one of the most valuable resources you can have when learning about yoga to lose weight.

Get My Free Ebook


Post a comment