• Headache and compromised or loss of vision caused by the prolactin-secreting tumor and its close proximity to the optic structures.
• Clinical presentation is associated with the degree of prolactin elevation:
• Prolactin greater than 100 ng/mL (100 mcg/L): hypogonadism, galactorrhea, and amenorrhea
• Prolactin 51 to 75 ng/mL (51-75 mcg/L): oligomenorrhea (infrequent menstruation).
• Increased body weight may be associated with prolactin-secreting pituitary tumor.
• The degree of hypogonadism generally is proportionate to the degree of prolactin elevation.
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