Sleep assessment

Blood pressure monitoring

■ r "id : ÏD^r^lo- (.:'" ■: did artery children in whom GH deficiency is suspected. Numerous pharmacologic agents such as insulin-induced hypoglycemia, levodopa, arginine, arginine plus levodopa, argin-ine plus GHRH, clonidine, and glucagon have been used to stimulate the pituitary to produce GH. However, no single test perfectly predicts GH deficiency or displays 100% sensitivity and specificity. 3 Additionally, administration of each of these tests is associated with adverse effects requiring close medical supervision. Further, current abnormal cutoffs to determine diagnosis are arbitrarily defined and lack universal con-

32 33

sensus. ' With further studies, these diagnostic criteria are likely to evolve and become more accurate. In prepubertal children, measurement of IGF-I concentrations may be useful in evaluating GH deficiency, with 100% specificity and 70% to 90% sensitivity.34 In children, the diagnosis of GH deficiency is further supported if height is more than two standard deviations below the population mean (age- and sex-

matched). Failure of linear growth is an almost universal presenting feature of childhood GH deficiency.

Stop Headache Drug Free

Stop Headache Drug Free

If you are suffering from headaches, you can make the pain stop just by following some basic but little known principles. Take 15 minutes browsing through this guide and you'll find dozens of tips to gain control in the battle against headache pain.

Get My Free Audio Book

Post a comment