Symptoms

• The patient may present with weakness, malaise, bleeding, and weight loss.

• Neutropenic patients are often febrile and highly susceptible to infection.

• Anemia usually presents as pallor, tiredness, and general fatigue.

• Patients with thrombocytopenia usually present with bruising, petechiae, and ec-chymosis.

• Chloromas (localized leukemic deposits named after their color) may be seen, especially in the periorbital regions and as skin infiltrates.

• Gum hypertrophy is indicative of AML M4 and AML M5 subtypes.

• Disseminated intravascular coagulation is common in AML M3 and is associated with generalized bleeding or hemorrhage.

• Lymphadenopathy, massive hepatosplenomegaly, and bone pain are not as common in AML as in ALL.

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