T Lymphocytes

The development and activation of T lymphocytes are important to maintain protection from infection without causing harm to the host.9 Activation of mature T lymphocytes requires two signals. The first is the presentation of an antigen by antigen-presenting cells to the T-lymphocyte receptor. Second, a ligand-receptor complex (i.e.,

CD80/CD86) on antigen-presenting cells binds to CD28 receptors on T lymphocytes. Once a cell successfully passes through all stages, the inflammatory cascade is activated.10 Activation of T lymphocytes: (a) stimulates the release of macrophages or monocytes, which subsequently causes the release of inflammatory cytokines; (b) activates osteoclasts; (c) activates the release of matrix metalloproteinases or enzymes responsible for the degradation of connective tissue; and (d) stimulates B lymphocytes and the production of antibodies.4,9

Anxiety and Depression 101

Anxiety and Depression 101

Everything you ever wanted to know about. We have been discussing depression and anxiety and how different information that is out on the market only seems to target one particular cure for these two common conditions that seem to walk hand in hand.

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